Pancreatic Beta Cell Identity is Maintained by DNA Methylation-Mediated Repression of ArxFriday, 9 September 2011 at 11:15 Add to Calendar ▼2011-09-09 11:15:002011-09-09 12:15:00Europe/LondonPancreatic Beta Cell Identity is Maintained by DNA Methylation-Mediated Repression of ArxEpigenetics Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com Arx is methylated and repressed in beta cells, and gets hypo-methylated and expressed in Dnmt1-deficient beta cells, DNA methylation propagates the transcriptional repression of Arx during beta cell replication, deletion of Dnmt1 results in reprogramming of beta cells to alpha cell. |