Uropathogenic E. coli Infection Leads to CDKN2A (p16INK4A) Hypermethylation in Uroepithelial CellsThursday, 8 September 2011 at 16:00 Add to Calendar ▼2011-09-08 16:00:002011-09-08 17:00:00Europe/LondonUropathogenic E. coli Infection Leads to CDKN2A (p16INK4A) Hypermethylation in Uroepithelial Cells Epigenetics Europe in MunichMunichSELECTBIOenquiries@selectbiosciences.com Recently, H.pylori infection of the stomach has been correlated with epigenetic changes in the host genome. To identify epigenetic changes during E.coli induced urinary tract infection (UTI), we developed an in vitro model of persistent infection of human uroepithelial cells with uropathogenic E.coli (UPEC) resulting in intracellular bacteria colonies without inducing host cell apoptosis. |