James Flanagan's Biography

James Flanagan, Research Fellow, Imperial College London

Dr James Flanagan, completed his PhD in 2002 at QIMR, and has pursued postdoctoral work in Cancer Genetics, Epigenetics and Cancer Epigenetics. He is currently leading his own group as a Breast Cancer Campaign Scientific Fellow in the Epigenetics Unit, Dept of Surgery and Cancer, Imperial College London. He was awarded the British Association of Cancer Research Translational Researcher Award in 2011. Current research is aimed at investigating epigenetic alterations as a mechanism for carcinogenesis, including projects to define tumour subgroups, identification of biomarkers for cancer risk or prognosis in breast and ovarian cancer and investigating the mechanism of transcriptional regulation by DNA methylation outside of the classical promoter CpG Island. Recent work has focussed on the hypothesis that epigenetic variation may be a driver of cancer risk whether by inherent constitutional variation or as a mediator of other cancer risk factors.