Sazid Hussain,
Research Assistant Professor,
Sanford Burnham Prebys Medical Discovery Institute
Research Assistant Professor 04/2018-Present Sanford Burnham Prebys Med Institute (SBP), La Jolla, San Diego, USA I have been employing in vivo phage-display to screen peptide libraries to identify new homing peptides and disease-specific biomarkers in traumatic brain injury, Alzheimer’s disease and bacterial infections. These newly identified peptides are currently being employed for imaging and delivery of therapeutics with nanoparticles.
CSO & Co-Founder 02/2016-Present AivoCode Inc, La Jolla, CA, USA The main focus area is on developing novel platforms to enable directed delivery of therapeutics into brain injuries.
Research Specialist (with Prof. Erkki Ruoslahti) 07/2014-03/2018 Sanford Burnham Prebys Med Institute (SBP), La Jolla, San Diego, USA
Scientist II (Project Leader) 11/2011-5/2014 Invictus Oncology, New Delhi, INDIA
Postdoctoral Fellow (with Prof. Erkki Ruoslahti) 12/2008-10/2011 Sanford-Burnham Medical Research Institute at Univ. of California, Santa Barbara, USA
PhD in Biochemistry 9/2001-12/2007 Biochemistry Institute, University of Zürich, Switzerland Advisors: Prof. Andreas Pluckthun and Prof. Uwe Zangemeister-Wittke
Peptides As Disease-Specific Probes For Targeted Drug Delivery
Tuesday, 18 February 2020 at 16:00
Add to Calendar ▼2020-02-18 16:00:002020-02-18 17:00:00Europe/LondonPeptides As Disease-Specific Probes For Targeted Drug DeliveryEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com
Ligand-directed (synaphic) targeting is a therapeutic strategy that makes use of antibodies, peptides, small molecules, or other moieties that bind to molecular receptors specifically expressed in diseased tissues. Screening of phage display libraries in vivo identifies peptides that recognizes molecular changes at the diseased site. This method has been found to be a powerful and unbiased method to discover peptides that specifically home to diseased tissues, such as tumors, atherosclerotic plaques, tissue injuries, and sites of bacterial infection. The combination of nanoparticle delivery with specific tissue targeting peptides provides a particularly powerful means of improving drug delivery. Such a targeting strategy can therefore potentially improve the efficacy of drugs and reduce their side effects.
Add to Calendar ▼2020-02-17 00:00:002020-02-18 00:00:00Europe/LondonEV-based Diagnostics, Delivery and TherapeuticsEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2020-02-18 16:00:002020-02-18 17:00:00Europe/LondonPeptides As Disease-Specific Probes For Targeted Drug DeliveryEV-based Diagnostics, Delivery and Therapeutics in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com
