| Conferences \ Extracellular Vesicles 2022: Technologies Driving Biological Investigations \ Agenda \ Terry Morgan |
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Placental Cell-Specific Extracellular Vesicle (EV) Changes Throughout Gestation Quantitated by Nanoscale Flow CytometryTuesday, 13 December 2022 at 10:30  Add to Calendar ▼2022-12-13 10:30:002022-12-13 11:30:00Europe/LondonPlacental Cell-Specific Extracellular Vesicle (EV) Changes Throughout Gestation Quantitated by Nanoscale Flow CytometryExtracellular Vesicles 2022: Technologies Driving Biological Investigations in Long Beach, CaliforniaLong Beach, CaliforniaSELECTBIOenquiries@selectbiosciences.comPlacental alkaline phosphatase (PLAP) positive EVs increase with gestational age and may be relatively increased early in pregnancy in women who develop severe pregnancy complications. Importantly, PLAP alone is not specific for placental EVs and multiplex antibody labeling is required to measure cell-specific events in plasma. We employ nanoscale high resolution flow cytometry to reliably image, count, and isolate cell- and size-specific EVs in banked plasma. This is the first study to demonstrate that most of the PLAP+ EV events in pregnant plasma arise from EVTs, not floating villi. |
Add to Calendar ▼2022-12-12 00:00:002022-12-14 00:00:00Europe/LondonExtracellular Vesicles 2022: Technologies Driving Biological InvestigationsExtracellular Vesicles 2022: Technologies Driving Biological Investigations in Long Beach, CaliforniaLong Beach, CaliforniaSELECTBIOenquiries@selectbiosciences.com
