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SELECTBIO Conferences Exosomes-EV-based Therapeutics Summit

Christine Happel's Biography



Christine Happel, Scientific Program Manager, National Center for Advancing Translational Sciences (NCATS)

Dr. Happel is the Scientific Program Manager for the NIH Extracellular RNA Communication Program. Dr. Happel has a Ph.D. in molecular biology and genetics from Temple University School of Medicine. She did postdoctoral fellowships at Johns Hopkins University and NCI, focusing on microRNA mediated regulation of gene expression in cancer. She also previously served as the Assistant Project Director for the NIH AIDS Reagent Program.

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The NIH Extracellular RNA Communication Consortium: Advancing Knowledge and Technologies for Extracellular RNA Research

Friday, 1 November 2019 at 12:00

Add to Calendar ▼2019-11-01 12:00:002019-11-01 13:00:00Europe/LondonThe NIH Extracellular RNA Communication Consortium: Advancing Knowledge and Technologies for Extracellular RNA ResearchExosomes-EV-based Therapeutics Summit in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

The discovery that secreted RNA (exRNA) is transported between cells through extracellular vesicles (EVs) suggested that exRNAs plays an important role in intercellular communication. Moreover, exRNAs also have utility as biomarkers of disease and as therapeutic agents. However, many gaps in knowledge and technical challenges in EVs and exRNA biology, such as mechanisms of EV biogenesis and uptake, exRNA cargo selection, and exRNA function. Moreover, efficient and reproducible methods for isolation and analysis of EVs and exRNAs were not available. The NIH Common Fund-supported exRNA Communication Consortium (ERCC) was launched in 2013 to address the major scientific challenges in this field. Participating laboratories from the 30 funded ERCC projects have worked individually and collaboratively to work toward these goals. This presentation will highlight the ERCC tools and resources developed, and scientific highlights particularly in biomarker discovery and therapeutic development of EV-based exRNA.


Add to Calendar ▼2019-11-01 00:00:002019-11-01 00:00:00Europe/LondonExosomes-EV-based Therapeutics SummitExosomes-EV-based Therapeutics Summit in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com