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SELECTBIO Conferences Extracellular Vesicles 2023: Drug Delivery, Biologics & Therapeutics

Shannon Holliday's Biography



Shannon Holliday, Associate Professor of Orthodontics and Anatomy & Cell Biology, University of Florida

Shannon Holliday is an Associate Professor of Orthodontics and Anatomy & Cell Biology at the University of Florida. He received his B.S. in Biology from West Virginia Tech, and a PhD in Cell Biology from the Florida State University focused on the crawling motility of nematode sperm. He continued his training as a postdoctoral fellow at the NIH in the lab of Edward D. Korn studying regulation of actin polymerization. During a second postdoc at Washington University in St Louis, he was introduced to osteoclasts and the vacuolar H+-ATPase (V-ATPase) in the laboratory of Stephen L. Gluck. He focused on the V-ATPase and the cytoskeleton in osteoclasts for many years. He became interested in extracellular vesicles (EVs) in 2013, and his group published one of the first articles on regulatory EVs released by osteoclasts in 2016. He is currently seeking strategies to develop new types of bone anabolic therapies based on EVs.

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Stimulating Production of Osteoclast-derived Regulatory Extracellular Vesicles to Therapeutically-control Bone Remodeling

Thursday, 27 July 2023 at 17:45

Add to Calendar ▼2023-07-27 17:45:002023-07-27 18:45:00Europe/LondonStimulating Production of Osteoclast-derived Regulatory Extracellular Vesicles to Therapeutically-control Bone RemodelingExtracellular Vesicles 2023: Drug Delivery, Biologics and Therapeutics in Orlando, FloridaOrlando, FloridaSELECTBIOenquiries@selectbiosciences.com

Osteoclasts produce extracellular vesicles (EVs) that stimulate bone formation by osteoblasts. Our recent data suggest that the production of these EVs can be increased experimentally.  We are now seeking to dissect the regulatory pathways that are involved. The goal is to therapeutically-stimulate osteoclasts to produce EVs that promote bone formation. Such agents could prove more useful than current therapeutics for treating bone diseases, or repairing bone defects.


Add to Calendar ▼2023-07-26 00:00:002023-07-27 00:00:00Europe/LondonExtracellular Vesicles 2023: Drug Delivery, Biologics and TherapeuticsExtracellular Vesicles 2023: Drug Delivery, Biologics and Therapeutics in Orlando, FloridaOrlando, FloridaSELECTBIOenquiries@selectbiosciences.com