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SELECTBIO Conferences Fragment Based Lead Discovery

Alessio Ciulli's Biography



Alessio Ciulli, BBSRC David Phillips Fellow, University of Cambridge

After graduating in Chemistry in 2002 from his hometown Florence under the late Ivano Bertini, Alessio obtained his PhD in 2006 from the University of Cambridge under the supervision of Chris Abell, and in collaboration with Astex Therapeutics. Following post-doctoral research on fragment-based drug design of tuberculosis enzymes with Chris Abell & Tom Blundell, and a short HFSP Fellowship at Yale University with Craig Crews, Alessio was awarded a BBSRC David Phillips Fellowship to return to Cambridge and started his independent career in January 2010. He will take up a Readership in Chemical & Structural Biology at Dundee University in 2013. Research in the Ciulli Lab focuses on Chemical and Structural Biology of Protein-Protein Interactions.

Alessio Ciulli Image

Dissecting Fragment-Based Lead Discovery at Protein-Protein Interfaces: The pVHL:HIF1a Interaction as a Case Study

Wednesday, 20 March 2013 at 09:30

Add to Calendar ▼2013-03-20 09:30:002013-03-20 10:30:00Europe/LondonDissecting Fragment-Based Lead Discovery at Protein-Protein Interfaces: The pVHL:HIF1a Interaction as a Case StudySELECTBIOenquiries@selectbiosciences.com

I will present our experiences investigating what fragment screening does and does not reveal about the tractability of a model PPI target site for inhibition by lead-like small molecules. 


Add to Calendar ▼2013-03-19 00:00:002013-03-20 00:00:00Europe/LondonFragment Based Lead Discovery SELECTBIOenquiries@selectbiosciences.com