From Improving Known Reactions to the Discovery of New Reactivity Exploiting FlowTuesday, 26 March 2024 at 14:30 Add to Calendar ▼2024-03-26 14:30:002024-03-26 15:30:00Europe/LondonFrom Improving Known Reactions to the Discovery of New Reactivity Exploiting FlowFlow Chemistry European Summit 2024 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com Through reactor miniaturization flow chemistry offers superb control over reaction conditions and thus lends itself towards the safe generation and immediate consumption of high-energy intermediates that would not be viable in analogous batch reactions. Our group1-5 and others have exploited this advantage to improve both the yield and selectivity of a number of synthetically important transformations. This talk will showcase several flow reactions including lithiations and photochemical processes that demonstrate the value of flow in this context, for instance for the generation and use of benzynes, acyl radicals and [1.1.1]propellane. The discovery of new chemical space aid by flow synthesis will be discussed as well. |