Conferences \ European Lab Automation \ Screening Europe - HCS and Assays \ Agenda \ Wendy Lea |
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A Strategy to Discover Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) as Anti-Cancer AgentsFriday, 1 July 2011 at 09:00 Add to Calendar ▼2011-07-01 09:00:002011-07-01 10:00:00Europe/LondonA Strategy to Discover Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) as Anti-Cancer AgentsSELECTBIOenquiries@selectbiosciences.com Tdp1 is a DNA repair enzyme, and its inhibitors can potentiate the efficacy of certain anti-cancer agents. A strategy to discover novel Tdp1 inhibitors is presented, including the development of a qHTS AlphaScreen assay and secondary assays for hit triaging. |