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SELECTBIO Conferences Liquid Biopsies 2019

Kun Zhang's Biography

Kun Zhang, Professor, Department of Bioengineering, University of California San Diego

Dr. Kun Zhang is a Professor of Bioengineering in the University of California at San Diego. After obtaining his Ph.D. in Human and Molecular Genetics from the University of Texas at Houston/MD Anderson Cancer Center, he received his post-doctoral training with George Church at Harvard Medical School. He joined the faculty of UCSD Department of Bioengineering in 2007. His current group is developing molecular techniques and engineering platforms for building single-cell maps of multiple human organs. Dr. Zhang became an elected fellow of AIMBE in 2017, and started to serve as Department Chair in 2018.

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Early Cancer Detection in Plasma by Methylation Haplotyping

Wednesday, 27 March 2019 at 16:00

Add to Calendar ▼2019-03-27 16:00:002019-03-27 17:00:00Europe/LondonEarly Cancer Detection in Plasma by Methylation HaplotypingLiquid Biopsies 2019 in Coronado Island, CaliforniaCoronado Island,

Adjacent CpG sites in mammalian genomes tend to be co-methylated due to the processivity of enzymes responsible for adding or removing the methyl group. This pattern, called methylation haplotypes, can be utilized to detect low levels of circulating DNA from tumor or tumor-residing tissues in the blood. We have developed NGS-based targeted methylation sequencing assays for early detection and location of multiple cancer types in the plasma. In this talk I’ll discuss the underlying principles and present the results on over 3000 samples from multiple cohorts.

Add to Calendar ▼2019-03-27 00:00:002019-03-29 00:00:00Europe/LondonLiquid Biopsies 2019Liquid Biopsies 2019 in Coronado Island, CaliforniaCoronado Island,