Hirofumi Shintaku's Biography

Hirofumi Shintaku, Professor, Institute for Life and Medical Sciences, Kyoto University

Hirofumi Shintaku is Professor at the Institute for Life and Medical Sciences, Kyoto University, and RIKEN Hakubi Team Leader. He has received numerous awards, including the Young Engineers Award from the Japan Society of Mechanical Engineers, the highest honor for young mechanical engineers. His current research focuses on technology development for single-cell biology leveraging electrokinetics in micro and nanoscale and integrating phenotyping and single-cell omics.

Nanoscale Electrokinetics Empowers Mechano Phenotyping of Single Cells

Thursday, 7 November 2024 at 14:30

Add to Calendar ▼2024-11-07 14:30:002024-11-07 15:30:00Europe/LondonNanoscale Electrokinetics Empowers Mechano Phenotyping of Single CellsLab-on-a-Chip, Microfluidics, and Organ-on-a-Chip Asia 2024 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com

Nanopore electroporation uses nanostructures to create focused electric fields, which form pores in lipid bilayers of living cells with low invasiveness. We introduce ELASTomics, an approach that parallelly profile cell surface tension and gene expression of thousands of single cells leveraging nanopore electroporation and single-cell RNA-sequencing. We show that our system dissects the heterogeneity in cellular mechanics and uncovers the transcriptomic regulatory mechanism in cancer malignancy, cell differentiation, and cellular senescence.

Add to Calendar ▼2024-11-07 00:00:002024-11-08 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics, and Organ-on-a-Chip Asia 2024Lab-on-a-Chip, Microfluidics, and Organ-on-a-Chip Asia 2024 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com

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