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SELECTBIO Conferences Lab-on-a-Chip, Microfluidics & Microarrays World Congress

Aaron Wheeler's Biography



Aaron Wheeler, Canada Research Chair of Bioanalytical Chemistry, University of Toronto

Aaron Wheeler completed his Ph.D. in Chemistry in 2003, working with Dick Zare at Stanford University. After graduating, Aaron spent two years as an NIH postdoctoral fellow at UCLA. Click here for links to Aaron's pre-Toronto publications. Since 2005, Aaron has been the Canada Research Chair of Bioanalytical Chemistry at the University of Toronto. Aaron is fortunate to work with a phenomenal (and prolific) research group -- their success has led to international recognition including the Arthur F. Findeis Award from the American Chemical Society and the Joseph Black Award from the Royal Society of Chemistry.

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Towards Point-of-Care Analysis Using Digital Microfluidics

Tuesday, 29 September 2015 at 09:00

Add to Calendar ▼2015-09-29 09:00:002015-09-29 10:00:00Europe/LondonTowards Point-of-Care Analysis Using Digital MicrofluidicsLab-on-a-Chip, Microfluidics and Microarrays World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

There is great enthusiasm in the microfluidics community for the development of “lab on a chip” systems for portable, point-of-care (POC) analysis. A major challenge in such applications is sample preparation—in particular, bridging the gap from the macro-scale of clinical specimens to the micro-scale of efficient fluidics/detection. The last decade has seen important advances in this area, but most systems today are either (a) very simple, with modest capability to integrate sophisticated sample processing protocols, or (b) require extensive off-chip ancillary equipment to operate (pumps, valves, tubes, interconnects, etc.). In this talk, I will present work towards an alternative scheme for POC analysis that relies on "digital microfluidics” (DMF). In DMF, droplets of sample and reagents are manipulated electrostatically on open devices (with no channels) bearing an array of electrodes covered with a hydrophobic insulator. DMF has the potential to address the challenges described above, allowing for sophisticated, multi-step sample processing on devices that operate with minimal external resources. I will highlight two different applications: on-chip immunoassays for diagnosing infectious diseases (including congenital rubella syndrome) and portable mass spectrometry-based quantitation of drugs of abuse for workplace testing. These examples and others suggest that digital microfluidics may be a useful new tool in the area of POC analysis.


Add to Calendar ▼2015-09-28 00:00:002015-09-30 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarrays World CongressLab-on-a-Chip, Microfluidics and Microarrays World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com