Shopping Cart (0)
My Account

Shopping Cart
SELECTBIO Conferences Lab-on-a-Chip and Microfluidics World Congress 2024

Roger Kamm's Biography



Roger Kamm, Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering, Massachusetts Institute of Technology (MIT)

Kamm is currently the Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering at MIT, where he has served on the faculty since 1978. Kamm has long been instrumental in developing research activities at the interface of biology and mechanics, formerly in cell and molecular mechanics, and now in engineered living systems. Current interests are in developing models of healthy and diseased organ function using microfluidic technologies, with a focus on vascularization, metastatic cancer and neurological disease. Kamm has fostered biomechanics as Chair of the US National Committee on Biomechanics (2006-2009) and of the World Council on Biomechanics (2006-2010). For 10 years, he was Director of the NSF Science and Technology Center on Emergent Behaviors of Integrated Cellular Systems. He is the 2010 recipient of the ASME Lissner Medal and the 2015 recipient of the Huiskes Medal, both for lifetime achievements, and was the inaugural recipient of the ASME Nerem Medal for mentoring and education. He was elected to the National Academy of Medicine in 2010 and Engineering in 2022. Kamm is co-founder of AIM Biotech, a manufacturer of microfluidic systems for 3D culture.

Roger Kamm Image

Brain Neurovascular Models and Their Application to Modeling Transport in Health and Disease

Monday, 18 November 2024 at 16:15

Add to Calendar ▼2024-11-18 16:15:002024-11-18 17:15:00Europe/LondonBrain Neurovascular Models and Their Application to Modeling Transport in Health and DiseaseLab-on-a-Chip and Microfluidics World Congress 2024 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Despite recent FDA approval of two drugs to reduce amyloid beta (A-beta) plaque in Alzheimer’s patients, a true cure of the disease remains elusive since they simply reduce the rate of cognitive decline.  Also, there is a need for deeper understanding of drug and toxin transport across the blood-brain barrier (BBB), which is difficult to obtain from animal experiments or human testing.  To meet this need, a variety of in vitro microphysiological models have been developed that can accurately recapitulate the barrier properties of the brain vasculature in the context of A-beta clearance from, and toxin or drug entry into, brain tissues.  This talk will focus on a progression of models developed to mimic both the healthy and diseased brain and to predict transport properties.  Cells used in these models can be either primary or iPS cell-derived with the latter being increasingly used to produce standardized models with greater consistency over time and appropriate for screening by pharma and biotech companies.


Add to Calendar ▼2024-11-18 00:00:002024-11-20 00:00:00Europe/LondonLab-on-a-Chip and Microfluidics World Congress 2024Lab-on-a-Chip and Microfluidics World Congress 2024 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com