Andrew Patterson's Biography

Andrew Patterson, Assistant Professor, Penn State University

At the Pennsylvania State University as part of the Center for Molecular Toxicology and Carcinogenesis, the Patterson lab is focused on understanding the host-metabolite-microbiome axis—specifically how the manipulation of gut bacteria through xenobiotic exposure or the use of gnotobiotic mouse models impacts bile acid pools, their metabolism, and how they interact with host nuclear receptors. The lab employs a variety of cutting-edge tools, including 1H NMR- and mass spectrometry-based metabolomics, metagenomics/metatranscriptomics, and conventional and gnotobiotic transgenic mice, to facilitate its study of these pathways and understand their impact on human health and disease.