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SELECTBIO Conferences Metabomeeting 2014

Andrew Southam's Biography



Andrew Southam, PostDoc Fellow, University of Birmingham

Dr Andy Southam is a Postdoctoral Fellow at the University of Birmingham. His research focuses on lipid metabolism in the leukaemia cell and aims to understand how metabolic perturbations to lipid biosynthesis affect cell survival. Current research involves identifying drug redeployment therapies (using currently available drugs for different purposes to their original intended use) that have anti-leukemic and anti-lymphomic activity by interfering with the cancer cell lipid metabolism.
He has a PhD in environmental and analytical metabolomics from the University of Birmingham. He has published several metabolomics papers relating to both biological studies and analytical method development, including the development of the SIM-stitch direct infusion FT-ICR mass spectrometry based metabolomics method. His areas of expertise are mass spectrometry metabolomics and lipidomics, cell biology and molecular biology.

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A Combination of Redeployed Drugs Demonstra Potent Anti-leukaemia and Anti-lymphoma Activity through Disruption of Tumour Cell de Novo Lipogenesis

Thursday, 11 September 2014 at 15:00

Add to Calendar ▼2014-09-11 15:00:002014-09-11 16:00:00Europe/LondonA Combination of Redeployed Drugs Demonstra Potent Anti-leukaemia and Anti-lymphoma Activity through Disruption of Tumour Cell de Novo LipogenesisMetabomeeting 2014 in London, UKLondon, UKSELECTBIOenquiries@selectbiosciences.com

The anti-leukemic therapy of bezafibrate and medroxyprogesterone acetate decreases lipogenesis in leukaemia and lymphoma cells. Lipogenic disruption is important for the anti-cancer activity of the treatment and is mediated by alteration of key enzymes in fatty acid synthesis.


Agenda is not currently available
Add to Calendar ▼2014-09-10 00:00:002014-09-12 00:00:00Europe/LondonMetabomeeting 2014Metabomeeting 2014 in London, UKLondon, UKSELECTBIOenquiries@selectbiosciences.com