microRNAs and their Exosomal Transfer Support Multiple Myeloma PathogenesisThursday, 9 May 2013 at 16:30 Add to Calendar ▼2013-05-09 16:30:002013-05-09 17:30:00Europe/LondonmicroRNAs and their Exosomal Transfer Support Multiple Myeloma PathogenesisSELECTBIOenquiries@selectbiosciences.com microRNAs play a pivotal role in modulating multiple myeloma (MM) biology. It is known that cell-to-cell communication is partially mediated by exosomes. However, it has not been conclusively demonstrated the role of bone marrow mesenchymal stromal cell (BM-MSC)-derived exosomes in supporting hematologic tumor growth and progression, through transfer of their microRNA content to the tumor clone. We therefore dissected the role of exosomal BM-MSC-microRNAs in regulating MM pathogenesis. |