Dong Pyo Kim,
Changjiang Scholar, Intelligent Microfluidics for Advanced Theranostics Lab,
Harbin Institute of Technology, China
Prof. Kim is a Yangtze River chair professor of HIT-Shenzhen, leading to innovative microfluidics for advanced theranostics from 2025, by shifting from POSTECH in Korea. He obtained a Ph.D. in chemistry and a postdoctoral degree in materials engineering, and worked at a national lab and a university for over 30 years in total, since 1993. His career in microfluidic-based continuous-flow synthetic processes encompasses the manufacturing of APIs and bespoke drug delivery systems, as well as the recent development of AI-based autonomous and integrated processes for biopharmaceuticals. He has published 350 peer-reviewed papers and 50 patents. He received the Academic Excellence Award (2017, Korean Chemical Society), Severo Ochoa Visiting Fellowship (2017, Spain), the POSTECHIAN of the Year (2016, POSTECH), The Scientist of the Month (2016, NRF), Yonsan chaired professor (POSTECH,2017), Henry McGee Lecturer (Virginia State Univ, 2021).
Microfluidic Encapsulation of Therapeutic Agents in Microdroplets and Nanoparticles
Wednesday, 14 December 2022 at 08:00
Add to Calendar ▼2022-12-14 08:00:002022-12-14 09:00:00Europe/LondonMicrofluidic Encapsulation of Therapeutic Agents in Microdroplets and NanoparticlesOrganoids and Microphysiological Systems 2022 in Long Beach, CaliforniaLong Beach, CaliforniaSELECTBIOenquiries@selectbiosciences.com
Microdroplets (µ-droplet) and nanoparticles (NPs) have been attracted significant interest in the past decades to address different drug delivery challenges, including poor bioavailability, poor drug solubility, and lack of targeted delivery. Traditionally, µ-droplet and NPs are often produced using bulk methods. In comparison, microfluidics offers a new strategy for making µ-droplet and NPs with controlled shape and homogeneous size due to rapid mass transfer and precise control over reaction conditions. Herein, we present a continuous-flow method for effectively encapsulating various therapeutic agents (enzymes, chelators, magnetic nanoparticles, bio-imaging agents, etc.) into uniform size of polymeric µ-droplet and inorganic NPs by microfluidics. Furthermore, we controlled the mixing time between the reactants of carrier and the therapeutic agent by forming various flow patterns (chaotic, multiple-laminar flow) and developed a drug delivery system with an improved therapeutic effect through flow control. This work will contribute effective encapsulation of therapeutic agents in µ-droplet and NPs, which would be extended to biomedical applications.
Add to Calendar ▼2022-12-12 00:00:002022-12-14 00:00:00Europe/LondonOrganoids and Microphysiological Systems 2022Organoids and Microphysiological Systems 2022 in Long Beach, CaliforniaLong Beach, CaliforniaSELECTBIOenquiries@selectbiosciences.com