CANCELLED - Osteoarticular Regenerative NanoMedicineFriday, 12 April 2013 at 14:15 Add to Calendar ▼2013-04-12 14:15:002013-04-12 15:15:00Europe/LondonCANCELLED - Osteoarticular Regenerative NanoMedicine Nanomedicine 2013 in Barcelona, SpainBarcelona, SpainSELECTBIOenquiries@selectbiosciences.com Recently, we have reported a "Smart Hybrid Materials Equipped by Nanoreservoirs of Therapeutics". This unique nanotechnology strategy is used to entrap, protect, and stabilize therapeutic agents into polymer coatings acting as nanoreservoirs enrobing nanofibers of implantable membranes. Upon contact with cells, therapeutic agents become available through enzymatic degradation of the nanoreservoirs. As cells grow, divide, and infiltrate deeper into the porous membrane, they trigger slow and progressive release of therapeutic agents that, in turn, stimulate further cell proliferation. This constitutes the first instance of a smart living nanostructured hybrid membrane for regenerative medicine. The cell contact-dependent bioerodable nanoreservoirs described here will permit sustained release of drugs, genes, growth factors, etc., opening a general route to the design of sophisticated cell-therapy implants capable of robust and durable regeneration of a broad variety of tissues. |