Comparative Analysis of Transposase, Endonuclease, and Physical Shearing Methods for Constructing Next-Generation DNA Sequencing LibrariesTuesday, 26 April 2011 at 11:15 Add to Calendar ▼2011-04-26 11:15:002011-04-26 12:15:00Europe/LondonComparative Analysis of Transposase, Endonuclease, and Physical Shearing Methods for Constructing Next-Generation DNA Sequencing LibrariesNext-Gen Sequencing Congress in BostonBostonSELECTBIOenquiries@selectbiosciences.com A comparison of libraries made by enzymatic or mechanical fragmentation reveals a slightly greater insertion bias, though this has little practical impact on genomic coverage, GC bias, and library complexity based on high-coverage sequencing of human, insect, and bacterial genomes. |