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SELECTBIO Conferences Organ-on-a-Chip and Body-on-a-Chip: In Vitro Systems Mimicking In Vivo Functions

Michael Moore's Biography



Michael Moore, Professor of Biomedical Engineering, Tulane University and Co-Founder, AxoSim

Michael J. Moore, PhD, is a Professor of Biomedical Engineering in Tulane University's School of Science and Engineering. He is also the Co-Founder and Chief Science Officer of AxoSim, a creator of the Nerve-on-a-Chip platform that is developing disease models for neurogenerative diseases such as neurotoxicity, amyotrophic lateral sclerosis, and multiple sclerosis. His academic research focuses on developing in vitro models of neural growth, physiology, and disease by manipulating the chemical and physical extracellular microenvironment. Toward this end, his lab employs a number of microengineering technologies such as microscale tissue engineering, novel nanomaterials, digital light projection lithography, and bioprinting. Dr. Moore received his B.S. in Biological Systems Engineering from the University of Nebraska and his PhD in Biomedical Engineering from Mayo Clinic College of Medicine and Science. After postdoctoral research at the Massachusetts Institute of Technology and Schepens Eye Research Institute, he joined the faculty of the Department of Biomedical Engineering at Tulane University, where he has been since 2007. He and his wife Lisa and their three daughters live in the Broadmoor neighborhood near Tulane’s undergraduate campus in New Orleans, LA.

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Development and Applications of a Peripheral Nerve-on-a-Chip

Tuesday, 11 July 2017 at 09:30

Add to Calendar ▼2017-07-11 09:30:002017-07-11 10:30:00Europe/LondonDevelopment and Applications of a Peripheral Nerve-on-a-ChipSELECTBIOenquiries@selectbiosciences.com

Development of microphysiological models of the nervous system have lagged that of other organ systems, perhaps because the most relevant anatomical features of the nervous system involve complex architecture, while relevant functional endpoints are electrophysiological in nature. In particular, peripheral nerve has been under-studied even though it is highly susceptible to systemic toxicity owing to its location outside the blood-brain barrier and its long axons situated distant from cell bodies in the CNS. The design and development of a peripheral nerve-on-a-chip is presented, which features relevant tissue architecture and functional metrics that are analogous to clinical gold-standard histomorphometry and nerve conduction testing. Applications to peripheral neurotoxicity and peripheral nerve disorders are discussed with illustrative examples using rodent and human cells.


Add to Calendar ▼2017-07-10 00:00:002017-07-11 00:00:00Europe/LondonOrgan-on-a-Chip and Body-on-a-Chip: In Vitro Systems Mimicking In Vivo FunctionsSELECTBIOenquiries@selectbiosciences.com