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SELECTBIO Conferences Organ-on-a-Chip and 3D-Culture: Companies, Technologies and Approaches
Conferences  \  Organ-on-a-Chip World Congress & 3D-Culture 2017  \  Organ-on-a-Chip and 3D-Culture: Companies, Technologies and Approaches  \  Agenda  \  Alicia Henn
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Alicia Henn's Biography


Alicia Henn, Chief Scientific Officer, BioSpherix, Ltd.

Alicia Henn is Chief Scientific Officer of BioSpherix, Ltd. She holds a PhD in Molecular Pharmacology and Cancer Therapeutics from Roswell Park Cancer Institute (2000). She also holds an MBA (2013) from University of Rochester, where she was a B cell biologist at the Center for Biodefense Immune Modeling. She is an inventor with patents from her work at RPCI, University of Rochester, and BioSpherix. Alicia writes the company blog, Cytocentric, and is also the founder/owner of the In Vitro Reproducibility Group on LinkedIn. Her research program focuses on physiologically relevant in vitro cell environments for reducing the time, money, and animals used to get novel therapeutics to the humans that need them.

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Effective Separation of the BioPrinting Atmosphere from Room Air for Protection of Tissue Constructs

Tuesday, 11 July 2017 at 11:00

Add to Calendar ▼2017-07-11 11:00:002017-07-11 12:00:00Europe/LondonEffective Separation of the BioPrinting Atmosphere from Room Air for Protection of Tissue ConstructsSELECTBIOenquiries@selectbiosciences.com

Valuable cell and tissue constructs are highly vulnerable to microbial contamination from room air exposure. Placing bioprinters and other cell and tissue-handling equipment in clean rooms and standard biological safety cabinets (BSC) can reduce risks, however there is still bioburden introduced by human operators, even in cleanroom garb. The Xvivo GMP System® barrier isolator separates the cell handling environment from room air with a soft, flexible glovefront. Filtered, tanked, medical grade gases provide a completely controlled and aseptic internal environment for any biomanufacturing process. There is no mixing of room air with the cellular environment. We set out to determine whether effective separation of the room air from the bioprinting environment could reduce contamination of biomanufactured constructs. Using the INKREDIBLE 3D Bioprinter by CELLINK, we bioprinted test samples inside and outside of the Xvivo System and incubated the constructs in a color-changing highly permissive TSB broth for a minimum of five days. We found that enclosing the bioprinting process inside the Xvivo System eliminated contamination from the constructs and the equipment. We conclude that effective separation of the bioprinting atmosphere from the laboratory room air decreases contamination risks for both biomanufacturing equipment and cell and tissue products.

Add to Calendar ▼2017-07-10 00:00:002017-07-11 00:00:00Europe/LondonOrgan-on-a-Chip and 3D-Culture: Companies, Technologies and ApproachesSELECTBIOenquiries@selectbiosciences.com


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