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SELECTBIO Conferences Organ-on-a-Chip and 3D-Culture: Companies, Technologies and Approaches

Brad Dykstra's Biography



Brad Dykstra, Senior Research Scientist, Platelet BioGenesis; Brigham and Women’s Hospital and Harvard Medical School

Brad Dykstra has studied stem cells of various flavors throughout his scientific career, including his PhD studies at the University of British Columbia in Vancouver (Canada) and subsequent post-doctoral fellowships in Groningen (the Netherlands) and Boston (USA). Currently he is a senior research scientist at the Brigham and Women’s Hospital Division of Hematology, as well as Platelet BioGenesis, a biotechnology start-up focused on the generation of iPSC-derived human platelets for donor-independent transfusion.

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Derivation of Functional Human Platelets from Induced Pluripotent Stem Cell-derived Megakaryocytes Using a 3D-Microfluidic Bioreactor

Tuesday, 11 July 2017 at 14:00

Add to Calendar ▼2017-07-11 14:00:002017-07-11 15:00:00Europe/LondonDerivation of Functional Human Platelets from Induced Pluripotent Stem Cell-derived Megakaryocytes Using a 3D-Microfluidic BioreactorSELECTBIOenquiries@selectbiosciences.com

To produce donor-independent platelets applicable for clinical use, we are advancing a serum-free and feeder-free protocol to generate functional megakaryocytes from human induced pluripotent stem cells. Human platelets can be efficiently produced from these megakaryocytes using our scalable microfluidic bioreactor that uses shear forces to trigger platelet production from these cells. Further scale-up of our device will enable cost-effective production of clinically relevant quantities of platelets, facilitating progression towards clinical trials.


Add to Calendar ▼2017-07-10 00:00:002017-07-11 00:00:00Europe/LondonOrgan-on-a-Chip and 3D-Culture: Companies, Technologies and ApproachesSELECTBIOenquiries@selectbiosciences.com