Jean-Manuel Segura,
Professor,
University of Applied Sciences and Arts Western Switzerland Valais
Jean-Manuel Segura is a professor of chemistry at the University of Applied Sciences Western Switzerland since 2008. He obtained his Ph.D. in 2000 from ETH Zürich in physical chemistry followed by post-doctoral and group leader positions at Leiden University, at EPFL and at the Ludwig Institute. His current research interests include the development of novel paper-based point-of-care in vitro diagnostic tests and the design and application of novel “smart” sensor molecules such as supramolecular biosensors or molecularly-imprinted polymers.
Paper-based Analytical Devices for Therapeutic Drug Monitoring at the Point of Care
Thursday, 10 September 2020 at 17:30
Add to Calendar ▼2020-09-10 17:30:002020-09-10 18:30:00Europe/LondonPaper-based Analytical Devices for Therapeutic Drug Monitoring at the Point of CarePoint-of-Care, Biosensors and Mobile Diagnostics Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Therapeutic Drug Monitoring (TDM) allows for personalized dosage during therapeutic treatments and is often mandatory for modern potent drugs against cancer, infections or in organ transplantation cases. TDM can be performed either based on the analysis of a biomarker such as cholesterol testing in case of statin treatments or based on a quantification of the therapeutic drug itself. A prototypical example is the antibiotics tobramycin, which is often prescribed to neonates in case of bacterial infection and requires TDM to ensure efficacy while avoiding oto- and nephrotoxicity. Currently, the process of TDM is demanding for the patient as several milliliters of blood are required, is slow and costly due to the transfer of sample to a central laboratory, and suffers of limited efficacy owing to the difficulty to interpret the results for a non-specialist. Paper offers many advantages as a material to produce IVD tests as it is cheap, amenable for mass manufacturing, easy to dispose after performing the test and it provides many functionalities for designing a test such as capillary-driven motion of liquids. I will present our most recent results in developing various paper-based IVD tests for therapeutic drug monitoring at the point of care. A particular emphasis will be put on micro-PAD tests for the monitoring of therapeutic antibiotics in the blood and for the joint analysis of glucose and cholesterol.
Add to Calendar ▼2020-09-09 00:00:002020-09-10 00:00:00Europe/LondonPoint-of-Care, Biosensors and Mobile Diagnostics Europe 2020Point-of-Care, Biosensors and Mobile Diagnostics Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2020-09-10 17:30:002020-09-10 18:30:00Europe/LondonPaper-based Analytical Devices for Therapeutic Drug Monitoring at the Point of CarePoint-of-Care, Biosensors and Mobile Diagnostics Europe 2020 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
