Micro- and Nano-scale Technologies for Applications in Medicine at the POCThursday, 18 September 2014 at 17:45 Add to Calendar ▼2014-09-18 17:45:002014-09-18 18:45:00Europe/LondonMicro- and Nano-scale Technologies for Applications in Medicine at the POCPoint-of-Care Diagnostics World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com Micro/nano-scale technologies can have a significant impact on medicine and biology in the areas of cell manipulation, diagnostics and monitoring. At the convergence of these new technologies and biology, we research for enabling solutions to the real world problems at the clinic. Emerging nano-scale and microfluidic technologies integrated with biology offer innovative possibilities for creating intelligent, mobile medical lab-chip devices that could transform diagnostics and monitoring, tissue engineering and regenerative medicine. In this talk, we will present an overview of our laboratory's work in these areas focussed on applications in point-of-care and primary care settings including applications for ovarian cancer detection from urine, rapid CD4 counts for global health, multiple pathogen detection with a focus on viral load from unprocessed whole blood and bedside peritonitis detection for end-stage kidney disease patients going through peritoneal dialysis therapy. We will also review our work on 3-D biofabrication/bioprinting, and dynamic acoustic and magnetic systems for bottom-up tissue-construct assembly using cell encapsulating microscale hydrogels to engineer the 3-D cellular microenvironment. As an example, we will present a microfluidic platform, where flow induces a motile and aggressive phenotype in ovarian cancer nodules via increased epithelial-to-mesenchymal transition (EMT). These emerging technologies could shape our future creating broadly applicable platforms for scientific discovery, providing clinical solutions for resource-constrained settings in the developing world as well as for primary care settings in the developed world. |