Maturation and Function of Long Noncoding RNA SPRY4-IT1 in Human MelanomasTuesday, 4 September 2012 at 09:30 Add to Calendar ▼2012-09-04 09:30:002012-09-04 10:30:00Europe/LondonMaturation and Function of Long Noncoding RNA SPRY4-IT1 in Human MelanomasSELECTBIOenquiries@selectbiosciences.com Recently, we reported that the long noncoding RNA SPRY4-IT1, which is transcribed from the intronic region of the Sprouty4 gene, is upregulated in human melanomas compared to melanocytes and keratinocytes (Khaitan et al., 2011 Cancer Research). We report here that SPRY4-IT1 is part of a larger (1.8Kb) noncoding RNA variant (SPRY4-IT) and 5’ region of this transcript is removed during the nuclear RNA processing. |