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SELECTBIO Conferences RNAi & miRNA

Alex Chenchik's Biography



Alex Chenchik, President/CSO, Cellecta Inc

Dr. Alex Chenchik, President/CSO of Cellecta, also a visiting scientist at the Harvard School of Public Health, started Cellecta in 2006. Alex was VP of R&D at System Biosciences, where he developed and commercialized the first genome-wide shRNA libraries, and Director of R&D for the Gene Cloning and Analysis group at Clontech/BD from 1994 to 2002.  Alex received his Molecular Biology Ph.D. from the Institute of Molecular Biology, Moscow, Russia in 1983 and was a scientist at the National Cardiology Research Center in Moscow from 1983-1994.  He has authored 44 publications and is an inventor on 10 issued patents.

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Viability Screens with Pooled shRNA Libraries Identify Novel and Synthetically Lethal Anti-Cancer Targets

Thursday, 19 April 2012 at 14:15

Add to Calendar ▼2012-04-19 14:15:002012-04-19 15:15:00Europe/LondonViability Screens with Pooled shRNA Libraries Identify Novel and Synthetically Lethal Anti-Cancer TargetsSELECTBIOenquiries@selectbiosciences.com

We identified and confirmed hundreds of genes modulating proliferation and survival in oncogenic cells using pooled lentiviral shRNA libraries. Also, we adapted and executed an approach to combinatorially screen shRNA to discover additive and synergistic combinations that are synthetically lethal.


Add to Calendar ▼2012-04-19 00:00:002012-04-20 00:00:00Europe/LondonRNAi and miRNASELECTBIOenquiries@selectbiosciences.com