NanoVelcro-Embedded Microchips for Detection and Isolation of Circulating Tumor Cells: Validation Studies in Oncology ClinicTuesday, 25 September 2012 at 10:00 Add to Calendar ▼2012-09-25 10:00:002012-09-25 11:00:00Europe/LondonNanoVelcro-Embedded Microchips for Detection and Isolation of Circulating Tumor Cells: Validation Studies in Oncology ClinicSingle Cell Analysis Summit in San Diego, USASan Diego, USASELECTBIOenquiries@selectbiosciences.com This presentation will introduce a new type of cell-affinity assay that is capable of detecting circulating tumor cells (CTCs) in blood samples collected from metastatic cancer patients. Similar to most of the existing approaches, anti-EpCAM was grafted onto the surfaces to distinguish CTCs from the surrounding hematologic cells. The uniqueness of our technology is the use of nanostructured surfaces, which facilitates local topographical interactionsbetween CTCs and substrates at the very first cell/substrate contacting time point. We demonstrated the ability of these nanostructured substrates to capture CTCs in whole blood samples with significantly improved efficiency and selectivity. |