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SELECTBIO Conferences Exosomes & Single Cell Analysis Summit

Hsian-Rong Tseng's Biography



Hsian-Rong Tseng, Professor, Crump Institute for Molecular Imaging, California NanoSystems Institute, University of California-Los Angeles

Dr. Tseng is professor in the Department of Molecular & Medical Pharmacology at UCLA. He also holds memberships of the California NanoSystems Institute, Crump Institute for Molecular Imaging and Institute for Molecular Medicine on the UCLA campus. Since he joined UCLA Pharmacology in 2003, Dr. Tseng’s group at UCLA has developed a series of nanotechnology- and microfluidics-enabled in vitro molecular diagnostic (IVMD) technologies. In collaboration with his physician colleagues, the goal of their joint team is to translate these new IVMD technologies from research bench to clinical practice.

Hsian-Rong Tseng Image

NanoVelcro-Based Single-Cell Genomics Verifies Surrogacy of Circulating Tumor Cells for Solid Tumor

Thursday, 18 September 2014 at 11:15

Add to Calendar ▼2014-09-18 11:15:002014-09-18 12:15:00Europe/LondonNanoVelcro-Based Single-Cell Genomics Verifies Surrogacy of Circulating Tumor Cells for Solid TumorExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

Our team at UCLA has demonstrated a highly efficient, inexpensive CTC assay (known as NanoVelcro Chips) capable of detecting and isolating circulating tumor cells (CTCs) in blood samples collected from metastatic cancer patients.  In addition to conducting CTC enumeration, we have been exploring the use of NanoVelcro Chips to isolate single CTCs without contamination by white blood cells (WBCs).  The individually isolated CTCs can then be subjected to molecular analysis by RT-PCR and next-generation sequencing, providing insights into tumor biology and heterogeneity and identify driver mutations that responsible to malignant transformation of cancer.  Moreover, the molecular profiling of CTCs may identify novel biomarkers that could guide the choice of therapies for individual patients as well as facilitate the development of new drugs.


Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonExosomes and Single Cell Analysis SummitExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com