Dr. Naomi Zurgil is co-establisher of the Biophysical Interdisciplinary Jerome Schottenstein Center (JSC) for the Research and Technology of the Cellome, and serves as head of biology and biochemistry division. Dr. Zurgil received her PhD in Biochemistry from Tel Aviv University and is author of over 70 scientific publications as well as several issued and pending patents. She is the recipient of awards, and grants from industrial, governmental and institutional sources. She served in various positions both in academia and in biotechnology industries. Her fields of expertise are: Cytometry, Cell and molecular biology, biochemistry, advanced tissue culture techniques, co -culturing, advanced in vitro cellular models, single cell analyses, live cell imaging, system biology, high content analysis, multi-parametric measurements, cell based drug screening, individual cell enzyme activity.
Live Cell Imaging-based Platforms for Single Cell/Element Time Lapse Measurements
Thursday, 18 September 2014 at 12:00
Add to Calendar ▼2014-09-18 12:00:002014-09-18 13:00:00Europe/LondonLive Cell Imaging-based Platforms for Single Cell/Element Time Lapse MeasurementsExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Individual living cells within a population may differ significantly and these differences can drive the health and function of the entire cell population. Live cell analysis of individual cells is a challenging endeavor due to the complexity of cell systems and cell motility. In the current study, we present novel methodologies and means for analyzing dynamic states of individual cells/group of cells, which enable monitoring alterations in cell behavior and function over time, in a complex tissue environment, and assessing functional changes at single cell level. This provides information on the physiology and the pathology status of a given cell, to be used in diagnosis and treatment of a spectrum of human diseases. The essential features of the above platforms are based on the concept of various types of arrays made of high-quality transparent micro-chambers, where each micro-chamber functions as a picoliter-well designed to hold a single cell or cell-aggregate without tethering. The technology is extremely flexible, using a spectrum of biomaterials having different characteristics, and the ability to control dimension, shape and distribution of the microstructures, as well as their configurations. This flexibility enables adaptation of the arrays to various cell types and use of both label-free and fluorescence detection methods to determine live cell status in real-time. The following practical applications of these unique cell-based platforms will be presented: [1]. Drug screening in 3D multicellular spheroids co-cultured with accessory cells; [2]. Cryopreservation of individual cells; [3]. Live cell measurement followed by cell content analysis of the same cells; and [4]. Single cell analysis of cell transfection and protein translocation.
Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonExosomes and Single Cell Analysis SummitExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2014-09-18 12:00:002014-09-18 13:00:00Europe/LondonLive Cell Imaging-based Platforms for Single Cell/Element Time Lapse MeasurementsExosomes and Single Cell Analysis Summit in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com
