Modified Mesenchymal Stromal Cells for Cell TherapyTuesday, 23 April 2013 at 15:30 Add to Calendar ▼2013-04-23 15:30:002013-04-23 16:30:00Europe/LondonModified Mesenchymal Stromal Cells for Cell TherapyClinical Translation of Stem Cells Summit in Palm Springs, CA, USAPalm Springs, CA, USASELECTBIOenquiries@selectbiosciences.com SB623 is an adult stem cell product derived from mesenchymal stromal cells (MSCs) by transient transfection with Notch-1. It has proven effective in a variety of models of neurodegenerative diseases. SB623 is not cell replacement therapy. It works by mechanisms including trophic support, production of beneficial extracellular matrix and immuno-modulation. A clinical trial has been initiated in patients with stable stroke deficits. This talk will focus on the immunological mechanism of action and the translation of this product from bench to clinic. |