Use of Mesenchymal Stem Cells for Therapies in the LungMonday, 24 January 2011 at 11:45  Add to Calendar ▼2011-01-24 11:45:002011-01-24 12:45:00Europe/LondonUse of Mesenchymal Stem Cells for Therapies in the LungStem Cells World Congress in San DiegoSan DiegoSELECTBIOenquiries@selectbiosciences.comWe have demonstrated that MSC administration prevented Acute and Chronic Lung Injury in animal models. Protection against injury is associated with regulation of immune after injury. We hypothesize that MSC may also can be use on lung transplantation by ameliorating the development of obliterative bronchiolitis (OB) during chronic rejection. The studies were performed in the mouse heterotopic allogenic airway transplant model. We transplanted mouse tracheas into genetically different mice strains. Treatment with MSC significantly reduced the epithelial loss and luminal occlusion after transplant. We will discuss the mechanisms described to explain the mechanism of action and the implications to translate MSC therapy into clinic. |
Add to Calendar ▼2011-01-24 00:00:002011-01-25 00:00:00Europe/LondonStem Cells World CongressStem Cells World Congress in San DiegoSan DiegoSELECTBIOenquiries@selectbiosciences.com
