Kevin Tabury,
Researcher,
Belgian Nuclear Research Centre
Kevin obtained a MSc. in biochemical engineering at Katholieke Universiteit Leuven, Belgium, while working at the radiobiology unit of the Belgian Nuclear Research Center (since 2009). He then obtained a PhD in biomedical engineering from the University of South Carolina, USA. Kevin is currently a researcher at the Radiobiology Unit of the Belgian Nuclear Research Center where he is working on several space and hadron therapy related projects. He leads the development of organ-on-chip with a focus on the cardiovascular system as well as cancer.
Space (Heart) Ship: A Heart-on-Chip Model to Study Cardiovascular Dysfunction in Space
Monday, 27 March 2023 at 16:00
Add to Calendar ▼2023-03-27 16:00:002023-03-27 17:00:00Europe/LondonSpace (Heart) Ship: A Heart-on-Chip Model to Study Cardiovascular Dysfunction in SpaceThe Space Summit Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
After two decades of human presence in orbit around Earth on the International Space Station (ISS), human settlement on the Moon and Mars is currently the next challenge to address in deep space exploration. Exiting the protection of our magnetosphere also lead to increase health risks from prolonged exposure to microgravity and space radiation that could seriously jeopardize space missions. Cardiovascular dysfunction and in particular accelerated cardiac aging is one of the concerns. Aging of the heart causes atherosclerosis, fibrosis, and reduced heart muscles contractility leading ultimately to heart failure. Despite our technological advances, the current molecular and cellular understanding of cardiovascular diseases because of aging is limited and mainly based on animal models. With an estimated radiation exposure of 0.5-1Sv for a manned mission to Mars, such increased cardiovascular risk becomes extremely relevant. In Space, the risks of cardiovascular diseases are also enhanced by microgravity. Thus, a deeper understanding of the biological mechanisms leading to cardiac aging is one of the key challenges in developing countermeasures. In this context, investigating the interplay between particle radiation and microgravity on cardiac aging in heart-on-chips becomes crucial. During this presentation, we will introduce our newest project and current advances in the development of a heart-on-chip model to study cardiovascular dysfunction in space.
Add to Calendar ▼2023-03-27 00:00:002023-03-28 00:00:00Europe/LondonThe Space Summit Europe 2023The Space Summit Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
Add to Calendar ▼2023-03-27 16:00:002023-03-27 17:00:00Europe/LondonSpace (Heart) Ship: A Heart-on-Chip Model to Study Cardiovascular Dysfunction in SpaceThe Space Summit Europe 2023 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com
