Conferences \ Discovery Chemistry Congress \ Targeting Protein-Protein Interactions \ Agenda \ Chiara Valenzano |
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The Development of Stapled Peptides that Modulate the BRCA2-RAD51 InteractionWednesday, 20 March 2013 at 15:45 Add to Calendar ▼2013-03-20 15:45:002013-03-20 16:45:00Europe/LondonThe Development of Stapled Peptides that Modulate the BRCA2-RAD51 InteractionSELECTBIOenquiries@selectbiosciences.com The interaction between the human recombinase RAD51 and the hub protein BRCA2 is crucial for the repair of double strand breaks via homologous DNA recombination. We designed and validated stapled peptides as chemical tools to unravel mechanistic aspects of this protein-protein interaction. |