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SELECTBIO Conferences Track Two

Yi-Chin Toh's Biography

Yi-Chin Toh, Assistant Professor, National University of Singapore

Yi-Chin Toh obtained her B.Eng in Chemical Engineering and PhD in Bioengineering from the National University of Singapore in 2001 and 2008 respectively. She did her post-doctoral training at the Massachusetts Institute of Technology in 2008 before joining the Institute of Bioengineering and Nanotechnology, A*STAR as a research scientist in 2010. Currently, she is an Assistant Professor with the Department of Biomedical Engineering in the National University of Singapore. Her research interest is in the application of microfluidics and BioMEMs to understand the spatio-temporal relationships between cellular microenvironments and stem cell fate specification during normal and pathogenic embryonic tissue patterning. These micro-engineered stem cell models will in turn be translated into scalable platforms for drug testing applications. Dr Toh is a recipient of the National University of Singapore Research Scholarship, A*STAR Graduate Scholarship and A*STAR International Fellowship.

Yi-Chin Toh Image

Micropatterned-Human Embryo (µ-HUE) Platform for Detection of Human Developmental Toxicity

Friday, 21 November 2014 at 15:05

Add to Calendar ▼2014-11-21 15:05:002014-11-21 16:05:00Europe/LondonMicropatterned-Human Embryo (µ-HUE) Platform for Detection of Human Developmental

This study presents a scalable human pluripotent stem cell (hPSC)-based screening platform to detect developmental toxicity in human. Using this in vitro model, we could not only measure dose-dependent effects but also correctly classify species-specific drug (Thalidomide) and false negative drug (D-Penicillamine) as compared to the leading in vitro mouse embryonic stem cell test.

Add to Calendar ▼2014-11-20 00:00:002014-11-21 00:00:00Europe/LondonTrack