Functional Roles of Tumor-derived Extracellular VesiclesSunday, 26 October 2014 at 17:15 Add to Calendar ▼2014-10-26 17:15:002014-10-26 18:15:00Europe/LondonFunctional Roles of Tumor-derived Extracellular VesiclesISEV2014 Educational Event in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com Extracellular vesicles (EVs) include distinct subtypes of lipid-enclosed particles. They are involved in intercellular communication in many physiological and pathological conditions, including cancer. Tumor-derived EVs contain functional protein and nucleic acid cargo, which may induce tumor-promoting effects in nearby tumor cells. They can also modulate different types of cells in the tumor microenvironment and prepare other organ types for metastasis. EV populations are heterogeneous in composition, size and functional roles. This complexity is likely in part a reflection of the dynamic nature of gene expression and signal transduction that manifests in cancer and other pathologic states. |