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SELECTBIO Conferences Extracellular Vesicles (EV)-Exosomes: Diagnostics, Delivery and Therapeutics

Sven Rudolf Kreutel's Biography



Sven Rudolf Kreutel, General Sales Manager, Particle Metrix GmbH

Sven Kreutel studied biology at the University of Hohenheim in Stuttgart, Germany. After his graduation in biology, he received his PhD in microbiology and protein biochemistry at the University of Hohenheim under Prof. Dr. Andreas Kuhn and Dr. Dorothee Kiefer working on the light sensing and signal transduction in photosynthetic bacteria. Since then he worked in different sales and sales manager positions within the life science industry from clinical research over biology to nanoparticle sciences.

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Know What’s In Your Sample: Phenotyping of Extracellular Vesicles (EVs) with Fluorescent Nanoparticle Tracking Analysis (f-NTA)

Thursday, 25 February 2021 at 14:00

Add to Calendar ▼2021-02-25 14:00:002021-02-25 15:00:00Europe/LondonKnow What’s In Your Sample: Phenotyping of Extracellular Vesicles (EVs) with Fluorescent Nanoparticle Tracking Analysis (f-NTA)Extracellular Vesicles (EV)-Exosomes: Diagnostics, Delivery and Therapeutics in Virtual ConferenceVirtual ConferenceSELECTBIOenquiries@selectbiosciences.com

In the last decade, Nanoparticle Tracking Analysis (NTA) has emerged as a vital and fast characterization technology for Extracellular Vesicles, Exosomes and Microvesicles. in the size range from 30 nm to 1 µm. While getting a particle size distribution, the user typically cannot discriminate whether the particle is a vesicle, protein aggregate, cellular trash or an inorganic precipitate from scatter data alone. The fluorescence detection capability of NTA enables the user to gain specific biochemical information about the particle surface and increases the resolution and the discrimination power. However, traditional NTA instruments are equipped with one laser wavelength in operation. This limits the detection of biomarkers to only a couple of fluorescence dyes. For change of excitation wavelength, it was necessary to change the laser source, a time and sample consuming step. To overcome this issue Particle Metrix developed a unique QUATT laser technology and now allows the rapid analysis of biomarker concentrations or ratios with four excitation lasers on the same sample. Here we report the multi-fluorescence detection of four independent biomarkers (CD63, CD81, CD9 and CD41) in one NTA sample with the new Particle Metrix ZetaView® QUATT for the first time.


Add to Calendar ▼2021-02-25 00:00:002021-02-26 00:00:00Europe/LondonExtracellular Vesicles (EV)-Exosomes: Diagnostics, Delivery and TherapeuticsExtracellular Vesicles (EV)-Exosomes: Diagnostics, Delivery and Therapeutics in Virtual ConferenceVirtual ConferenceSELECTBIOenquiries@selectbiosciences.com