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SELECTBIO Conferences Sample Preparation and Analysis

Kamlesh Patel's Biography

Kamlesh Patel, R&D Advanced System Engineering and Deployment Manager, Sandia National Laboratories

Dr. Kamlesh D. Patel is research scientist at Sandia National Laboratories-California and currently serves as the manager for the Advance Systems Engineering and Deployment Group. Dr. Patel’s research focus is part of a larger effort at Sandia to develop creative and innovative solutions to challenging and emerging issues in global chemical, biological, and radiological dangers?protecting our nation and troops abroad from such threats. An important element of Dr. Patel’s group is to improve our nation’s ability to anticipate and defend by developing advance concepts platforms for better detection and diagnostic capability to make rapid, real-time decisions. With a background in analytical separation science, coupled to years of experience in microsystems engineering, Dr. Patel has applied microfluidic-based technology and systems engineering to such new frontiers.

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Advanced Diagnostic and Sample Preparation Platform for Bio-surveillance

Tuesday, 24 March 2015 at 17:30

Add to Calendar ▼2015-03-24 17:30:002015-03-24 18:30:00Europe/LondonAdvanced Diagnostic and Sample Preparation Platform for

Emerging infectious diseases present a profound threat to global health, economic development, and political stability, and therefore represent a significant national security concern for the U.S. The key to preventing an outbreak before it goes global is to establish a biosurveillance network that effectively reaches even the most remote regions and provides a network-integrated, location-appropriate diagnostic capability. At present, the two main factors that prevent the extension of biosurveillance activities beyond centralized laboratory facilities are the lack of a deployable rapid-response diagnostic platform and a method to safely and consistently process infected samples in the field for analysis.  We report on our work to develop a forward-deployed sample preparation and diagnostic platform to safely and consistently process infected clinical samples in the field for analysis as part of a comprehensive biosurveillance strategy. Small-volume blood samples are processed on a digital microfluidic hub platform with integrated modules to 1) extract and process RNA and 2) stabilize and format RNA into a cDNA intermediate  for either real-time multiplex PCR analysis or lab-based next generation sequencing.

Add to Calendar ▼2015-03-23 00:00:002015-03-24 00:00:00Europe/LondonSample Preparation and