High Content Screening of an Antigen-Specific 3D Tumor-Spheroid/Primary T-cell Co-Culture SystemFriday, 5 October 2018 at 13:30 Add to Calendar ▼2018-10-05 13:30:002018-10-05 14:30:00Europe/LondonHigh Content Screening of an Antigen-Specific 3D Tumor-Spheroid/Primary T-cell Co-Culture System3D-Culture and Organoids in Coronado Island, CaliforniaCoronado Island, CaliforniaSELECTBIOenquiries@selectbiosciences.com Overcoming tumor-mediated immunosuppression and enhancing cytotoxic T-cell activity within the tumor microenvironment are two central goals of immuno-oncology (IO) drug discovery initiatives. Here we present a novel ultra-high-content assay platform for interrogating antigen-dependent T-cell-mediated killing of 3D tumor spheroids that yields multi-parametric, clinically-relevant data and can be employed kinetically for the discovery of novel IO therapeutic agents. |