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SELECTBIO Conferences Lab-on-a-Chip, Microfluidics & Microarray World Congress

Martyn Boutelle's Biography



Martyn Boutelle, Professor of Biomedical Sensors Engineering, Vice Chair Department of Bioengineering, Imperial College London

Martyn Boutelle is Professor of Biomedical Sensors Engineering, and Deputy Departmental Chair at the Department of Bioengineering, Imperial College London. His research group is genuinely multidisciplinary comprising, bioengineers, scientists and clinicians. He develops novel analytical science methods using microfluidics, electrochemical sensors and biosensors, and wireless electronics to make portable, wearable monitoring devices. He then uses these in a program of clinical science research focusing on the acute traumatic brain injury, kidney transplantation and athelete monitoring. The same measurement techniques are used in patients and in experimental models allowing genuine translational research. Professor Boutelle is a Fellow of the Royal Society of Chemistry. He obtained a BSc and PhD in Chemistry from Imperial College and worked as an EP Abraham Research Fellow in the University of Oxford.

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Microfluidic Devices for Real-Time Clinical Monitoring of Microdialysis Streams

Thursday, 18 September 2014 at 11:15

Add to Calendar ▼2014-09-18 11:15:002014-09-18 12:15:00Europe/LondonMicrofluidic Devices for Real-Time Clinical Monitoring of Microdialysis StreamsLab-on-a-Chip, Microfluidics and Microarray World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com

Microdialysis probes are an FDA approved way of sampling the molecular composition of human tissue including the brain, the low volume flow rates (0.2 – 2 µL / min) of microdialysis probes are ideal for linking to microfluidic analysis devices. Concentrations of key biomarker molecules can then be determined continuously using either electrochemically (using amperometric, and potentiometic sensors) or optically.  Droplet-based microfluidics, by digitizing the dialysis stream into discrete low volume samples,  (a) allows rapid concentration change to be detected without the effects of the temporal smearing caused by dispersion, and  (b) allows dialysate droplets to be quickly transported from the patient or surgical field to the analysis chip. This talk will describe the design, optimization, calibration and use of both droplet-based and continuous flow microfluidic analysis systems for clinical monitoring during reconstructive surgery and, for traumatic brain injury patients, extended monitoring of the brain in the intensive care unit.


Add to Calendar ▼2014-09-18 00:00:002014-09-19 00:00:00Europe/LondonLab-on-a-Chip, Microfluidics and Microarray World CongressLab-on-a-Chip, Microfluidics and Microarray World Congress in San Diego, California, USASan Diego, California, USASELECTBIOenquiries@selectbiosciences.com