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SELECTBIO Conferences Sample Preparation and Analysis

Mark Reed's Biography

Mark Reed, Professor, Yale University

Prof. Mark A. Reed received his Ph.D. in Physics from Syracuse University in 1983, after which he joined Texas Instruments. In 1990 Mark joined Yale University where he holds the Harold Hodgkinson Chair of Engineering and Applied Science. He was chairman of the Department of Electrical Engineering from 1995 to 2001. He is presently the Associate Director of the Yale Institute for Nanoscience and Quantum Engineering. Mark’s research activities have included the investigation of electronic transport in nanoscale and mesoscopic systems, artificially structured materials and devices, molecular scale electronic transport, plasmonic transport in nanostructures, and chem/bio nanosensors. Mark is the author of more than 200 professional publications and 6 books, has given over 25 plenary and over 370 invited talks, and holds 25 U.S. and foreign patents on quantum effect, heterojunction, and molecular devices. He is the Editor in Chief of the journal Nanotechnology and holds numerous other editorial and advisory board positions. Mark has been elected to the Connecticut Academy of Science and Engineering and Who's Who in the World. His awards include; Fortune Magazine “Most Promising Young Scientist” (1990), the Kilby Young Innovator Award (1994), the Fujitsu ISCS Quantum Device Award (2001), the Yale Science and Engineering Association Award for Advancement of Basic and Applied Science (2002), Fellow of the American Physical Society (2003), the IEEE Pioneer Award in Nanotechnology (2007), Fellow of the Institute of Electrical and Electronics Engineers (2009), and a Finalist for the World Technology Award (2010).

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The Physics and Applications of Nanoelectronic Biosensors

Tuesday, 24 March 2015 at 15:30

Add to Calendar ▼2015-03-24 15:30:002015-03-24 16:30:00Europe/LondonThe Physics and Applications of Nanoelectronic

Nanoscale electronic devices have the potential to achieve exquisite sensitivity as sensors for the direct detection of molecular interactions, thereby decreasing diagnostics costs and enabling previously impossible sensing in disparate field environments.  Semiconducting nanowire-field effect transistors (NW-FETs) hold particular promise, though contemporary NW approaches are inadequate for realistic applications and integrated assays.  We present here an integrated nanodevice biosensor approach that is compatible with CMOS technology, has achieved unprecedented sensitivity, and simultaneously facilitates system-scale integration of nanosensors.  These approaches enable a wide range of label-free biochemical and macromolecule sensing applications, such as specific protein and complementary DNA recognition assays, and specific macromolecule interactions at femtomolar concentrations.  Critical limitations of nanowire sensors are the Debye screening limitation and the lack of internal calibration for analyte quantification, which has prevented their use in clinical applications and physiologically relevant solutions.  We will present approaches that solve these longstanding problems, which demonstrates the detection at clinically important concentrations of biomarkers from whole blood samples, integrated assays of cancer biomarkers, and the use of these as a quantitative tool for drug design and discovery, including binding kinetics, chirality detection, enzyme detection, and activity.

Add to Calendar ▼2015-03-23 00:00:002015-03-24 00:00:00Europe/LondonSample Preparation and