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SELECTBIO Conferences RNAi & miRNA

Anja Hoeg's Biography



Anja Hoeg, Associate Director of Discovery, Santaris Pharma

Anja Mølhart Høg is a Ph.D. in Medical Science from the Faculty of Health Sciences at University of Copenhagen. She holds a M.Sc. in Biotechnology from the Technical University of Denmark. She has 5 years of experience from the pharmaceutical biotech and drug discovery industry. She currently serves as Group Leader, Partnered Technology at Santaris Pharma A/S, the Danish RNA medicines company. Santaris Pharma holds the world pharmaceutical patent rights to Locked Nucleic Acid (LNA). Dr. Høg has worked for more than a decade with RNA medicines and drug discovery using LNA.

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Therapeutic Antagonism of microRNAs with LNA: A Translational Research Modality

Thursday, 19 April 2012 at 17:00

Add to Calendar ▼2012-04-19 17:00:002012-04-19 18:00:00Europe/LondonTherapeutic Antagonism of microRNAs with LNA: A Translational Research ModalitySELECTBIOenquiries@selectbiosciences.com

LNA oligonucleotides are potent inhibitors of coding and non-coding RNA. SPC3649 is the first micro-RNA inhibitor in man and has shown safe and significant reduction in HCV viral load in patients. It will be illustrated in the talk how the clinical and pre-clinical data closely interrelate and how this has formed the basis for the fast and coherent development path of the drug. The SPC3649 case story suggests that LNA oligonucleotides targeting disease related microRNAs may enable translational research from bench to clinic.


Add to Calendar ▼2012-04-19 00:00:002012-04-20 00:00:00Europe/LondonRNAi and miRNASELECTBIOenquiries@selectbiosciences.com