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SELECTBIO Conferences Circulating Biomarkers World Congress 2016

Stefan Momma's Biography

Stefan Momma, Group Leader, University Hospital Frankfurt

Stefan Momma is a neuroscientist working in the Edinger Institute of the University Hospital Frankfurt. He received his training in biology and biochemistry in Germany and the UK before doing his PhD on neural stem cells and their role in brain injury at the Karolinska Institutet, Sweden. His interests include basic mechanisms in maintaining stem cell functions as well as selected aspects in the field of microvesicles and exosomes. For the latter, his work focuses on the role of exosomes in the communication between tissues in vivo, particularly the interaction between the immune system and the brain in the context of inflammatory reactions.

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Extracellular Vesicle-Mediated Transfer of Functional RNA Between Tissues

Monday, 21 March 2016 at 16:00

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Extracellular vesicles (EVs) emerge as important carriers for intercellular communication and they have been implicated in many biological processes. However, due to their small size and the difficulties of manipulating them, the data on EV biology has thus far been based mainly on in vitro or indirect in vivo evidence, or on experiments involving ex vivo manipulations. Furthermore, it is difficult to establish the exact cells of origin as well as individual cellular targets for in vivo experiments. Thus, the extent and pathogenic role of EV signalling in vivo, particularly with regard to the transfer of functional RNA, remains poorly understood. Using the Cre-Lox system we can overcome some of the major shortcomings in this field by establishing a method to trace the functional transfer of RNA by EVs in vivo.

Add to Calendar ▼2016-03-21 00:00:002016-03-22 00:00:00Europe/LondonCirculating Biomarkers World Congress 2016Circulating Biomarkers World Congress 2016 in Boston, USABoston,