Joanne Nettleship,
Senior Scientist,
University of Oxford
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Streamlining the Pipeline Towards Glycoprotein Structures
Thursday, 30 June 2011 at 17:00
Add to Calendar ▼2011-06-30 17:00:002011-06-30 18:00:00Europe/LondonStreamlining the Pipeline Towards Glycoprotein StructuresSELECTBIOenquiries@selectbiosciences.com
• High-throughput pipeline for glycoprotein production in HEK 293 cells.
• Parallelization and automation of expression screening.
• Glycan modification to aid glycoprotein crystallization.
• Automated large scale production and purification of secreted proteins.
• Use of transient transfection v’s formation of a stable cell line.
• Antibody Fab’s as co-crystallization chaperones.
• In situ diffraction for solving glycoprotein structures.