Engineering EVs for Cardiovascular Diseases

Wednesday, 3 April 2024 at 15:00

Add to Calendar ▼2024-04-03 15:00:002024-04-03 16:00:00Europe/LondonEngineering EVs for Cardiovascular DiseasesExtracellular Vesicles (EVs) and Nanoparticles 2024: Diagnostics, Delivery, Therapeutics in Miami, FloridaMiami, FloridaSELECTBIOenquiries@selectbiosciences.com

Extracellular vesicles derived from healthy sources contain natural homing properties and therapeutic cargo and can be leveraged as biomimetic carriers for targeted delivery. Additionally, extracellular vesicles represent an endogenous source of nanoparticles and can offer enhanced safety as a nanoparticle platform technology. In this presentation, EVs derived from healthy cells of the vasculature and their ability to be engineered as agents that inhibit vascular calcification and inflammation in atherosclerosis will be included. Strategies to enable EV surface modification and enhance cargo loading will be presented, and the potential of engineered EVs towards clinical applications will be discussed.

Eun Ji Chung, Dr. Karl Jacob Jr. and Karl Jacob III Early Career Chair, Associate Professor of Biomedical Engineering, Chemical Engineering and Materials Science, Surgery, and Medicine, University of Southern California

Eun Ji Chung

Eun Ji Chung is an Associate Professor in the Department of Biomedical Engineering at the University of Southern California and the Dr. Karl Jacob Jr. and Karl Jacob III Early Career Chair. She has a courtesy appointment in Chemical Engineering, Medicine (Nephrology and Hypertension), and Surgery (Vascular Surgery and Endovascular Repair), and is an affiliated faculty of the Norris Cancer Center and the Stem Cells department. Her laboratory is interested in developing nano- to macroscale biomaterials that can be utilized in medicine. Dr. Chung received her B.A. with honors in Molecular Biology from Scripps College, her Ph.D. from the Department of Biomedical Engineering from Northwestern University, and her postdoctoral training from the Pritzker School of Molecular Engineering at the University of Chicago.