Multicolor, High-Resolution Exosome Analysis with the Delaware Flow NanoCytometer

Thursday, 4 April 2024 at 11:00

Add to Calendar ▼2024-04-04 11:00:002024-04-04 12:00:00Europe/LondonMulticolor, High-Resolution Exosome Analysis with the Delaware Flow NanoCytometerExtracellular Vesicles (EVs) and Nanoparticles 2024: Diagnostics, Delivery, Therapeutics in Miami, FloridaMiami, FloridaSELECTBIOenquiries@selectbiosciences.com

The Delaware Flow NanoCytometer® is a particle analyzer that can measure from EVs to cells. It has a resolution of 6 nm, it can detect 28-nm gold, 60-nm polystyrene, and 68-nm liposomes. We have characterized HansaBioMed FLuoEVs (~90 nm) by scattering, membrane stain, expressed EGFP, and PE-conjugated tetraspanins (CD9, CD63, and CD81). We have benchmarked the Delaware against Particle Metrix’s ZetaView NTA, with close agreement on fluorescent fractions. The Delaware is designed for multiparameter analysis, with up to 6 channels of fluorescence and three scattering channels.

Giacomo Vacca, President & CEO, Kinetic River Corp

Giacomo Vacca

Giacomo Vacca, Ph.D., has physics degrees from Harvard (BA/MA) and Stanford (PhD). With Nobel Prize winner Bob Laughlin, he developed a novel ultrafast light scattering technique for his dissertation. He has been issued 77 patents to date. At Abbott Labs, Dr. Vacca invented and developed Laser Rastering, a radically innovative concept in flow cytometry that increased the rate of cell analysis by a factor of 30. In 2010 Dr. Vacca founded Kinetic River, a flow cytometry product development company. Since 2017, Kinetic River has been awarded five competitive Small Business Innovative Research (SBIR) grants from the NIH, totaling about $5M to date. Kinetic River's customers include NIH–NCI, Stanford, UC Davis, Italy's National Research Council, and enterprises from startups to Fortune 500 companies. Dr. Vacca is a past Abbott Research Fellow and a senior member of both SPIE and Optica, and is a member of the Editorial Advisory Board of BioPhotonics magazine.