SELECTBIO - Extracellular Vesicles & Cell-Free RNAs 2023 Biographies

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Liquid Biopsy Core (LBC) - Enabling Tools for the Isolation of Liquid Biopsy Markers and Their Molecular Analysis

Wednesday, 29 November 2023 at 17:30

Add to Calendar ▼2023-11-29 17:30:002023-11-29 18:30:00Europe/LondonLiquid Biopsy Core (LBC) - Enabling Tools for the Isolation of Liquid Biopsy Markers and Their Molecular AnalysisExtracellular Vesicles and Cell-Free RNAs 2023 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com

Liquid biopsies are minimally invasive tests that can be performed frequently, providing “real-time” information on disease status to improve patient outcome. Analyzing different biomarkers present in liquid biopsies, including circulating tumor cells (CTCs), cell-free DNA (cfDNA), and extracellular vesicles (EVs), requires enrichment to select the low abundant disease-associated markers from clinical samples. The LBC provides a diverse range of technologies that are directed at both enriching liquid biopsy markers and their downstream molecular analysis. The LBC uses a combination of microfluidics with full process automation for enriching the full complement of liquid biopsy markers with exquisite analytical figures-of-merit. As examples of utility of LBC technologies, we will present clinical data on identifying the molecular subtypes of breast cancer using EV’s mRNA and monitoring response to therapy in pancreatic cancer via CTCs.

Malgorzata Witek, Associate Research Professor, The University of Kansas

Dr. Malgorzata (Maggie) A. Witek is an Associate Research Professor at KU, Lawrence. Her research is focused on microfluidic-based isolation and solid-phase extractions of liquid biopsy markers, including circulating tumor cells, extracellular vesicles, and cell free DNA for stroke and cancer disease management. She shares her research efforts between the University of Kansas in the NIH/NIBIB funded Center of BioModular Multiscale Systems for Precision Medicine and the COBRE funded Kansas Institute for Precision Medicine at the University of Kansas Medical Center (KUMC). Maggie co-directs the Liquid Biopsy Core at KUMC campus.