SELECTBIO - Lab-on-a-Chip & Microfluidics World Congress 2023 Biographies

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Navigating the Winding Road of Inertial Focusing to the Clinic

Tuesday, 28 November 2023 at 17:40

Add to Calendar ▼2023-11-28 17:40:002023-11-28 18:40:00Europe/LondonNavigating the Winding Road of Inertial Focusing to the ClinicLab-on-a-Chip and Microfluidics World Congress 2023 in Laguna Hills, CaliforniaLaguna Hills, CaliforniaSELECTBIOenquiries@selectbiosciences.com

I will share a historical perspective exploring inertial microfluidic concepts, from the beginning in Mehmet Toner's Center for Engineering in Medicine, to its application for cell profiling using deformability cytometry at UCLA, to the recent FDA-clearance and clinical use of deformability cytometry as part of the IntelliSep test for early sepsis diagnosis. IntelliSep is the first FDA-cleared test for early sepsis diagnosis and the first test that employs biomechanical measurements of cells as a key marker of disease. The talk will highlight key aspects of matching microfluidic technology capabilities with clinical need, lessons learned in the journey from research lab to the clinic, and the importance of exploiting serendipity.

Dino Di Carlo, Armond and Elena Hairapetian Chair in Engineering and Medicine, Professor and Vice Chair of Bioengineering, University of California-Los Angeles

Dino Di Carlo received his B.S. in Bioengineering from the University of California, Berkeley in 2002 and received a Ph.D. in Bioengineering from the University of California, Berkeley and San Francisco in 2006. From 2006-2008 he conducted postdoctoral studies in the Center for Engineering in Medicine at Harvard Medical School. He has been on the faculty in the Department of Bioengineering at UCLA since 2008 and now as Professor of Bioengineering and Mechanical Engineering serves as the Vice Chair of the Department and as the director of the Cancer Nanotechnology Program in the Jonsson Comprehensive Cancer Center. His research pioneered the use of inertial fluid dynamic effects for the control, separation, and analysis of cells in microfluidic devices. His recent work extends into numerous other fields of biomedicine and biotechnology including directed evolution, cell analysis for rapid diagnostics, new amplified molecular assays, next generation biomaterials, and phenotypic drug screening. He has also been a leader in technology entrepreneurship: He co-founded and currently serves on the board of directors of five companies that are commercializing UCLA intellectual property developed in his lab (CytoVale, Vortex Biosciences, Tempo Therapeutics, Forcyte Biotechnologies and Ferrologix). Among other honors he received the Presidential Early Career Award for Scientists and Engineers (PECASE) and was elected a Fellow of the American Institute for Medical and Biological Engineering in 2016, was elected a Fellow of the Royal Society of Chemistry (FRSC) in 2014, was awarded the National Science Foundation (NSF) Faculty Early Career Development award and the U.S. Office of Naval Research (ONR) Young Investigator Award, the Packard Fellowship and Defense Advanced Research Projects Agency (DARPA) Young Faculty Award, and received the National Institutes of Health (NIH) Director’s New Innovator Award and Coulter Translational Research Award.