SELECTBIO - Microfluidics & Organ-on-a-Chip Asia 2019 Biographies

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On-the-Fly Optofluidic Imaging Platforms For Deep and Large-Scale Single-Cell Analysis

Friday, 15 November 2019 at 15:30

Add to Calendar ▼2019-11-15 15:30:002019-11-15 16:30:00Europe/LondonOn-the-Fly Optofluidic Imaging Platforms For Deep and Large-Scale Single-Cell AnalysisMicrofluidics and Organ-on-a-Chip Asia 2019 in Tokyo, JapanTokyo, JapanSELECTBIOenquiries@selectbiosciences.com

This talk will introduce our recently developed ultrafast optofluidic imaging techniques (multi-ATOM and FACED imaging) that practically allow ultralarge-scale single-cell imaging (>millions of adherent or suspended cells) in real-time with the unprecedented combination of imaging resolution and speed. These techniques generate multiple single-cell image contrasts from which not only deep single-cell biophysical and biomechanical phenotypic profiles can be obtained (based on quantitative phase and other label-free contrasts), but also biochemical signatures of single-cells (based on fluorescence contrast). Combined with high-performance computing hardware and high-throughput computational methods (particularly machine learning), their utilities in large-scale cell-based assays using cell-lines, in-vivo mouse models, as well as primary human cells (e.g. for circulating tumor cell detection, routine blood analysis, drug screen) will be discussed.

Kevin Tsia, Associate Professor, Department of Electrical & Electronic Engineering, The University of Hong Kong

Kevin Tsia received his Ph.D. degree at the Electrical Engineering Department, at University of California, Los Angeles (UCLA), in 2009. He is currently an Associate Professor in the Department of Electrical and Electronic Engineering, and the Program Director of the Biomedical Engineering Program, at the University of Hong Kong. His research interest covers a broad range of subject matters, including ultra-fast optical imaging for imaging flow cytometry and cell-based assay; high-speed in-vivo brain imaging; computational approaches for single-cell analysis. His pervious researches, such as energy harvesting in silicon photonics and the World’s fastest optical imaging system, have attracted worldwide press coverage and featured in many science and technology review magazines such as MIT Technology Review, EE Times and Science News. He received Early Career Award 2012-2013 by the Research Grants Council (RGC) in Hong Kong. He also received the Outstanding Young Research Award 2015 at HKU as well as 14th Chinese Science and Technology Award for Young Scientists in 2016. He is author or coauthor of over 180 journal publications, conference papers and book chapters. He holds 3 granted and 4 pending US patents on ultrafast optical imaging technologies. He is a co-founder of start-up company commercializing the high-speed microscopy technology for clinical diagnostic applications.