Utilization of Spheroid Microarrays in Cell Line Shipment

Tuesday, 25 June 2024 at 11:30

Add to Calendar ▼2024-06-25 11:30:002024-06-25 12:30:00Europe/LondonUtilization of Spheroid Microarrays in Cell Line ShipmentOrganoids and Spheroids Europe 2024 in Rotterdam, The NetherlandsRotterdam, The NetherlandsSELECTBIOenquiries@selectbiosciences.com

The shipment of cells and cell lines is associated with high costs and heavy packages because of the amount of dry ice that cells need to be shipped on, to maintain their viability. Arrived in the laboratory, cells are stored in liquid nitrogen and afterward, upon use it still happens that a great number of cells are not culturable. To tackle this issue, we combined microarray technology with multicellular spheroid culture. There we found that due to the compaction in small multicellular spheroids, apoptosis is inhibited over a prolonged period. Further, multicellular spheroids bear already in vivo-like features such as spatial organization, cell-cell interactions, and deposited extracellular matrix, that improve model quality and reliability for drug testing. With this novel shipment technology, we try to improve and standardize cell-based research.

Martin Frauenlob, Scientist, Cell Chip Group, TU-Vienna

Martin Frauenlob

Dr. Martin Frauenlob, a Scientist at the Cell Chip Group of the TU Wien, Vienna, holds a Ph.D. in Transdisciplinary Life Science from Hokkaido University. Under Dr. Jian Ping Gong he worked on biocompatibility and inducing pluripotency in cancer stem cells on soft matter. Later he contributed to the Biomaterials and Microfluidics core facility at Institute Pasteur, Paris, collaborating on multi-tissue microfluidic devices, which he continues at the TU Wien. In his team, he tries to target challenges in biotechnology and biomedicine by combining innovative microfluidics, biosensors, and cell culture.